Characterisation of cyclohexane hydroxylase; involvement of a cytochrome P-450 system from a cyclohexane grownXanthobactersp.
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چکیده
منابع مشابه
Involvement of Cytochrome P-450 in n-Butyl Nitrite-Induced Hepatocyte Cytotoxicity
Addition of n-butyl nitrite to isolated rat hepatocytes caused an immediate glutathione depletion followed by an inhibition of mitochondrial respiration, inhi- bition of glycolysis and ATP depletion. At cytotoxic butyl nitrite concentrations, lipid peroxidation occurred before the plasma membrane was disrupted. Cytochrome P-450 inhibitors inhibited peroxynitrite formation and prev...
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Cytochrome P-450 was purified to apparent homogeneity from the brain microsomes of phenobarbital-treated rats. The specific content of the purified P-450 was 12.7 nmol/mg of protein. NADPH-cytochrome P-450 reductase (reductase) was also purified to apparent homogeneity from brain microsomes. The specific content was 34.7,mol of cytochrome c reduced/min per mg of protein. The reduced carbon mono...
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چکیده ندارد.
15 صفحه اولinvolvement of cytochrome p-450 in n-butyl nitrite-induced hepatocyte cytotoxicity
addition of n-butyl nitrite to isolated rat hepatocytes caused an immediate glutathione depletion followed by an inhibition of mitochondrial respiration, inhi- bition of glycolysis and atp depletion. at cytotoxic butyl nitrite concentrations, lipid peroxidation occurred before the plasma membrane was disrupted. cytochrome p-450 inhibitors inhibited peroxynitrite formation and prevented ...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 1990
ISSN: 0378-1097,1574-6968
DOI: 10.1111/j.1574-6968.1990.tb03963.x